Objective(s):To date, the most important genes responsible for tetracycline resistance among Acinetobacter baumannii isolates have been identified as tet A and tet B. This study was carried out to determine the rate of resistance to tetracycline and related antibiotics, and mechanisms of resistance.  Materials and Methods: During the years 2010 and 2011, a total of 100 A. baumannii isolates we...

objective(s):to date, the most important genes responsible for tetracycline resistance among acinetobacter baumannii isolates have been identified as tet a and tet b. this study was carried out to determine the rate of resistance to tetracycline and related antibiotics, and mechanisms of resistance.  materials and methods: during the years 2010 and 2011, a total of 100 a. baumannii isolates wer...

conclusions the high prevalence of tet (o) resistance gene along with new detection of tet (a) resistance gene in campylobacter spp. isolated from poultry carcasses revealed an extensive tetracycline resistance among campylobacter isolates from poultry in iran. it emphasized the need for cautious use of tetracycline in poultry production to decrease the extension of tetracycline-resistant campy...

Five common tetracycline resistance genes tet(A), tet(B), tet(M), tet(O) and tet(S) were studied by polymerase chain reaction in 100 bacteria isolated from Iranian fish farms. In the antibiogram test most of the bacteria were either intermediately or completely resistant to tetracycline. Nine isolates out of 46 Aeromonas spp. contained eithe...

five common tetracycline resistance genes tet(a), tet(b), tet(m), tet(o) and tet(s) were studied by polymerase chain reaction in 100 bacteria isolated from iranian fish farms. in the antibiogram test most of the bacteria were either intermediately or completely resistant to tetracycline. nine isolates out of 46 aeromonas spp. contained either tet(a/m/s) resistant genes as follows: tet(a) in a. ...

Both domains, alpha and beta, of the cytoplasmic membrane-localized Tet proteins encoded by the tet gene family (classes A through E) are required for resistance to tetracycline (Tcr) in gram-negative bacteria. Two inactive proteins, each containing a mutation in the opposite domain, are capable of complementation to produce Tcr. Similarly, inactive hybrid proteins expressed by interdomain gene...

To investigate tetracycline resistance and resistant genotype in Riemerella anatipestifer, the tetracycline susceptibility of 212 R. anatipestifer isolates from China between 2011 and 2017 was tested. The results showed that 192 of 212 (90.6%) R. anatipestifer isolates exhibited resistance to tetracycline (the MICs ranged from 4 to 256μg/ml). The results of PCR detection showed that, 170 of 212...

Worldwide tetracycline resistance (Tc) is increasing dramatically, causing serious environmental and health problems. A total of 201 samples were collected from chicken intestine, human feces and treated sewage effluent (TSE). One hundred and eighteen Escherichia coli strains were isolated and identified using MALDI-Biotyper. Single and multiplex PCR were used to screen isolates for 14 tet gene...

Earlier studies have demonstrated the promising antitumor effect of tetrandrine (Tet) against a series of cancers. However, the poor solubility of Tet limits its application, while its hydrophobicity makes Tet a potential model drug for nanodelivery systems. We report on a simple way of preparing drug-loaded nanoparticles formed by amphiphilic poly(N-vinylpyrrolidone)-block-poly(ε-caprolactone)...